A fungus that attacks almond and peach trees may be key to identifying new drug targets for cancer therapy. A team of Florida State University researchers from the Department of Chemistry and Biochemistry found that a natural product from the fungus Fusicoccum amygdali stabilizes a family of proteins in the cell that mediate important signaling […]
Breakthrough synthesis strategy could mean wave of new medicinal compounds
In pharmacology, not all molecular structures are created equal. Some frameworks are overrepresented in nature, making them especially attractive to scientists on the hunt for more effective drugs. One such structure, known to scientists as the carbocyclic 5-8-5 fused ring system, is notoriously difficult to produce using conventional laboratory methods, and researchers have therefore been […]